Drug Uses
Premarin is indicated for treating symptoms of advanced breast cancer in selected men and women, treating or preventing a variety of symptoms due to menopause (hot flashes, vaginal itching, burning, dryness), preventing osteoporosis (brittle bones) after menopause, replacing estrogen after failure of the ovaries, and treating advanced prostate cancer in men. Premarin may be used for certain conditions, as determined by your doctor, which may not be listed in the professional package insert. If you have questions about how Premarin is being used, contact your doctor.

How Taken
Premarin should be taken with a meal. Take it at the same time every day. Talk to your doctor about the dosage suitable for you and discuss stopping taking Premarin 4 – 6 weeks before surgery.

Warnings/Precautions
Before taking Premarin, tell your doctor or pharmacist if you have any medical conditions, especially if you have allergies to medicines, foods, or other substances, if you have asthma (wheezing), a benign breast nodule, bone cancer, depression, diabetes, endometriosis or endometrial (uterine) cancer, epilepsy (seizures), gallbladder disease, heart problems, high blood pressure, kidney problems, liver problems or a history of yellowing of the skin or eyes, lupus, migraines, obesity, pancreatitis, uterine fibroids, thyroid problems or have high calcium levels in your blood, if you are using tobacco, you are going to have surgery, or you will be on bed rest, if you have a family history of high cholesterol, lipid, calcium, or triglyceride levels, or breast cancer, if you have abnormal mammogram, if you are pregnant, planning to become pregnant or are breast–feeding. Do not use Premarin if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. Premarin is excreted in breast milk. If you are or will be breast–feeding while you are taking Premarin, check with your doctor or pharmacist to discuss the risks to your baby. Some medicines may interact with Premarin, therefore tell your doctor of all prescription or nonprescription medicine, herbal preparation, or dietary supplement that you are taking. Do not take Premarin if you have known, suspected, or a history of breast cancer (unless directed by your doctor) or other cancers that are estrogen–dependent, have abnormal vaginal bleeding of unknown cause, have impaired liver disease, or the blood disease porphyria, had a stroke or heart attack within last year, have blood clots or circulation disorders. Smoking while taking Premarin may increase your risk of blood clots (especially in women older than 35 years of age). You doctor should reevaluate you every 3–6months to determine whether or not you need to continue taking Premarin. If you are being treated for vaginal menopause symptoms, products applied locally such as vaginal creams, tablets, or rings should be considered before products taken by mouth or absorbed through the skin. If you have other medical conditions and are prescribed estrogens for more than one condition, consult your doctor about your treatment plan and its options. Premarin may affect blood sugar levels. Premarin may cause dark skin patches on your face. Exposure to the sun may make these patches darker, and you may need to avoid prolonged sun exposure and sunlamps. Consult your doctor regarding the use of sunscreens and protective clothing. Premarin increases the chances of getting cancer of the uterus. Report any unusual vaginal bleeding right away while using Premarin. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your doctor should check any unusual vaginal bleeding to find out the cause. Lab tests, including a lipid profile, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments. Premarin may affect some lab tests results. Make sure laboratory personnel and your doctors know you use Premarin.

Missed Dose
If you miss a dose take it as soon as you remember. However if it is almost time for the next dose, skip the Missed Dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Possible Side Effects
Some of the Possible Side Effects are– Back pain, bloating, breast pain, depression, diarrhea, dizziness, flu syndrome, gas, hair loss, headache, increased cough, increased/decreased interest in sex, indigestion, infection, irregular vaginal bleeding or spotting, itching, joint pain, lightheadedness, leg cramps, muscle aches, nausea, nervousness, pain, runny nose, sinus inflammation, sleeplessness, sore throat, stomach pain, upper respiratory tract infection, vaginal inflammation, weakness, weight changes. Contact your doctor if any of these or other side effects occur. If you experience any of the following serious side effects, you should seek medical attention immediately– allergic reactions (rash, hives, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue), abnormal bleeding from the vagina, breast lumps, changes in vision or speech, chest pain, dizziness, fainting, mental/mood changes, pain or tenderness in the upper abdomen, pain in the calves, severe headache, sudden shortness of breath, swelling of the hands or feet, unusual vaginal discharge/itching/odor, vomiting, weakness or numbness of an arm or leg, yellowing of the skin or eyes.

Storage
Store Premarin at room temperature, between 68 – 77 °F (20 – 25 °C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Aygestin out of the reach of children.

Overdose
If overdose is suspected seek medical attention immediately. Symptoms may include excessive vaginal bleeding 2 to 7 days following overdose, nausea and vomiting.

More Information
Premarin may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Premarin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. If your symptoms do not improve or if they worsen, contact your doctor

Disclaimer
This is only general information, it does not cover all directions, drug integrations or precautions. You should not rely on it for any purpose, it does not contain any specific instructions for a particular patient. We disclaim all responsibility for the accuracy and reliability of this information. We`re not responsible for any damage.